Fortunato Depero (March 30, 1892 - November 29, 1960) was an Italian futurist painter, writer, sculptor and graphic designer.

Born in Fondo (in the Italian Trentino region), Depero grew up in Rovereto. In 1914 he moved to Rome and met fellow futurist Giacomo Balla. With Balla in 1915 that he wrote the manifesto Ricostruzione futurista dell’universo ("Futurist Reconstruction of the Universe") which expanded upon the ideas introduced by the other futurists.

In 1919 Depero founded the "Casa d'Arte Futurista" (House of Futurist Art) in Rovereto, which specialised in producing toys, tapestries and furniture in the futurist style.

In 1928 Depero moved to New York, where he experienced a degree of success, doing costumes for stage productions and designing covers for magazines including Movie Maker, The New Yorker and Vogue. In 1930 he returned to Italy.

In the 1930s and 40s Depero continued working, although due to futurism being linked with fascism, the movement started to wane. After the end of the Second World War, Depero had trouble with authorities in Europe and in 1947 decided to try New York again. From the winter of 1947 to late October 1949 Depero lived in a cottage in New Milford, Connecticut, relaxing and continuing with his long-standing plans to open a museum. His host was William Hillman, an associate of the then-President, Harry S. Truman.

After New Milford, Depero returned to Rovereto, where he would live out his days. In August 1959 Galleria Museo Depero opened, fulfilling one of his long-term ambitions. On November 29, 1960, after being ill with diabetes and spending the last two years unable to paint due to hemiparesis, Depero died age 68.

Many of his works are featured in the permanent collection of the Mart, the Museum of Modern and Contemporary Art of Trento and Rovereto. The Casa d'Arte Futurista Depero, Italy's only museum dedicated to the Futurist movement, and containing 3,000 objects is now one of Mart's venues. The Casa d'Arte Futurista Depero reopened on January 17 2009.